A senior researcher / group leader position is available immediately for a highly motivated individual to study neurobiology of aging by applying molecular and cellular biology, biochemistry and imaging methods in animal models and in vitro neuronal cultures.

Candidates must have a doctoral degree in neuroscience, electrophysiology, and biology of aging or related fields with strong quantitative skills. Technical expertise in cellular and molecular biology and neuroimaging and the ability to learn and develop new skills are required. Understanding of the basic concepts of aging and neurodegeneration is highly desirable. The successful candidate should have an advanced publication record, solid written/verbal English communication skills, strong organizational abilities, and be able to work independently.

The researcher is expected to lead and perform necessary functions which include design and planning projects, data collection, analysis and preparation of research manuscript for publication and writing grant proposals. The researcher will work within the Department of Experimental Neurobiology, National Institute of Mental Health, Czech Republic, under the leadership of Prof. Saak V. Ovsepian.

The department is equipped with cutting-edge research facilities for imaging (confocal microscopy and epifluorescence), molecular and cellular biology laboratories, neurochemistry, in vivo electrophysiology and behavioural studies in animals. It has eight research groups covering a wide range of neurobiology research. The National Institute of Mental Health is located in lovely suburb of Prague City, one of the most beautiful and vibrant cities of Europe.

Interested and qualified applicants are encouraged to apply by submitting

1) A cover letter outlining research accomplishments and career goals,

2) Curriculum vitae

3) A list of three references with contact information (including mailing address, phone number and e-mail address)


All documents should be submitted as a single PDF to Bc. Bukacova (Marcela.Bukacova@nudz.cz) before 15th of September 2019.




Ovsepian SV et al., Neurobiology and therapeutic applications of neurotoxins targeting transmitter release. Pharmacol Ther. 2018. doi: 10.1016/j.pharmthera.2019.08.016. IF=12.2

Ovsepian SV et al. Synaptic vesicle cycle and Aβ: biting the hand that feeds. Alzheimer’s and Dementia, 2018. doi: 10.1016/j.jalz.2018.01.011; 2018. IF=13.2

Ovsepian SV et al. Pushing the boundaries of neuroimaging with optoacoustics. Neuron 2017. doi: 10.1016/j.neuron.2017; IF 14.1

Ovsepian SV et al. Circumventing Brain Barriers: Nanovehicles for Retro-axonal Therapeutic Delivery. Trends in Mol. Medicine 2016; doi:10.1016/j.molmed.2016.09.004. IF: 10.8

Willem M et al. η-Secretase processing of APP inhibits neuronal activity in the hippocampus. Nature, 2015 Doi:10.1038 / 14864. IF: 38.1