Overview

We are seeking a highly motivated scientist for an EU-funded postdoctoral position in protein structural biology for an experimental team at Loschmidt Laboratories, Masaryk University, Brno, Czech Republic (https://loschmidt.chemi.muni.cz/peg/). We conduct basic research in enzymology and fight acute stroke, cancer and Alzheimer’s disease.

JOB DESCRIPTION:

  • Perform protein expression, purification and biophysical characterization
  • Design and perform protein crystallization experiments
  • Collect X-ray diffraction data and determine protein-ligand complex structures
  • Adapt emerging structural techniques: nanocrystallography and cryo-EM
  • Work in an friendly, inspiring and highly collaborative environment
  • Opportunities for further training, personal growth and benefits package

PROFILE OF CANDIDATE:

  • Ph.D. in structural biology, molecular biology, biochemistry or biophysics
  • Experience with protein expression and purification
  • Previous experience with protein structural techniques
  • Experience with biophysical and biochemical protein characterization
  • Willingness to learn new techniques: nanocrystallography and cryo-EM
  • Ability to develop new concepts; goal-oriented and problem-solving skills
  • Good proficiency in English

APPLICATIONS:

  • Curriculum Vitae and motivation letter
  • Two letters of recommendation
  • Send your application to Jitka Sedlackova at jitkasedlackova@mail.muni.cz

SELECTED PAPERS:

•J. Am. Chem. Soc. 140: 17999, 2018   ACS Catalysis 8: 9420, 2018
•J. Am. Chem. Soc. 137: 4988, 2015   ACS Catalysis 6: 7597, 2016
•Chem. Rev. 113: 5871, 2013    Curr. Opin. Chem. Biol. 19: 8, 2014
•Angewandte Chemie 52: 1959, 2013  Nature Chem. Biol. 10: 428, 2014